How does chronic kidney disease (CKD) progress?

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Chronic kidney disease (CKD) is characterized by a progressive and gradual decline in kidney function over time. This process usually occurs due to underlying conditions such as diabetes or hypertension, which cause damage to the kidneys. As CKD progresses, the glomerular filtration rate (GFR) decreases, resulting in an accumulation of waste products, electrolyte imbalances, and worsening health status for the individual. Eventually, if the decline continues unchecked, it can lead to end-stage renal disease (ESRD), where the kidneys can no longer function effectively. This understanding is critical for managing CKD, as it underlines the importance of early detection and management to potentially slow down the progression of the disease.

In contrast, the other options describe scenarios that do not accurately reflect the nature of CKD. Sudden kidney failure implies an acute event rather than chronic progression. Sporadic recoveries imply fluctuations in kidney function that are not typical of CKD, which is generally characterized by a steady decline. Regular monitoring and interventions can help manage CKD, but they do not prevent the gradual progression of the disease. Hence, option C accurately conveys the chronic nature of kidney disease progression.

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